Download: PHARMACODYNAMICS by Professor Fink

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Professor Fink reviews the Onset of Action, Duration of Action & Mechanisms of Action of Drugs. Affinity and Intrinsic Activity (Efficacy) at Receptor Sites is explained. Agonists (Mimetics) and Antagonists (Blockers) are explained. The Dose Response (Effect) Relationship is presented, including the difference between Potency and Efficacy (Intrinsic Activity). Biological Variation is described, including the ED50 and factors affecting Response. Clark's Rule is presented. The Placebo Effect is described, the Effects of Stress, Drug Tolerance (Tachyphylaxis) and Drug-Drug Interactions.

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